Description

2-Butenoic Acid, 4-(1H-Indol-6-Ylamino)-4-Oxo- is a specialized indole derivative with a reactive α,β-unsaturated carbonyl motif. This compound serves as a valuable high-purity building block for advanced organic synthesis, particularly in the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D and agrochemical research organizations seeking to create new chemical entities with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or plant growth regulators that leverage the indole scaffold.
• Bioconjugation & Probe Development: The reactive Michael acceptor site makes it suitable for creating fluorescent probes or protein-binding conjugates for biochemical studies.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers with unique electronic or photophysical properties.
• Academic & Contract Research: Serves as a critical reagent in university laboratories and CROs (Contract Research Organizations) for methodological studies and library synthesis.

Basic Information

Product Name	2-Butenoic Acid, 4-(1H-Indol-6-Ylamino)-4-Oxo-
CAS No.	939250-30-3
Molecular Formula	C₁₃H₁₂N₂O₃
Molecular Weight	244.25 g/mol
Synonyms	4-[(1H-Indol-6-yl)amino]-4-oxo-2-butenoic acid; 4-(1H-Indol-6-ylamino)-4-oxobut-2-enoic acid; (2E)-4-[(1H-Indol-6-yl)amino]-4-oxo-2-butenoic acid; 6-Aminoindole acrylamide derivative; 4-Oxo-4-(1H-indol-6-ylamino)but-2-enoic acid; (E)-4-(1H-Indol-6-ylamino)-4-oxobut-2-enoic acid; N-(1H-Indol-6-yl)fumaramic acid
EINECS	Contact for details

Quality Control

Our production of 2-Butenoic Acid, 4-(1H-Indol-6-Ylamino)-4-Oxo- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.