Description

1-(tert-Butyl) 2-Ethyl 6-Bromo-1H-Indole-1,2-Dicarboxylate is a high-purity, synthetically valuable brominated indole derivative. This compound serves as a critical protected intermediate in advanced organic synthesis, enabling the precise construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides with specific modes of action.
• Material Science: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Academic & Contract Research: Essential reagent for methodological studies in heterocyclic and medicinal chemistry within university and CRO laboratories.
• Peptidomimetics: The protected carboxylate groups make it suitable for constructing indole-based scaffolds that mimic peptide structures.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	1-(tert-Butyl) 2-Ethyl 6-Bromo-1H-Indole-1,2-Dicarboxylate
CAS No.	939045-17-7
Molecular Formula	C₁₇H₂₀BrNO₄
Molecular Weight	382.25 g/mol
Synonyms	6-Bromo-1H-indole-1,2-dicarboxylic acid 1-(1,1-dimethylethyl) 2-ethyl ester; Ethyl 6-bromo-1-[(tert-butoxy)carbonyl]-1H-indole-2-carboxylate; 6-Bromo-1-Boc-indole-2-carboxylic acid ethyl ester; 1-Boc-6-bromoindole-2-carboxylic acid ethyl ester; tert-Butyl 6-bromo-2-(ethoxycarbonyl)-1H-indole-1-carboxylate; 6-Bromoindole-1,2-dicarboxylic acid 1-tert-butyl 2-ethyl ester; Boc-6-Br-In-2-COOEt
EINECS	Contact for details

Quality Control

Our production of 1-(tert-Butyl) 2-Ethyl 6-Bromo-1H-Indole-1,2-Dicarboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. All material is characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.