Description

Piperidin-4-Yl(2-Thienyl)Methanol CAS NO 938458-94-7 is a sophisticated chiral building block and heterocyclic compound of significant interest in advanced organic synthesis. Its molecular architecture, featuring both piperidine and thiophene moieties, makes it a valuable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of potential new drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Asymmetric Synthesis: Serves as a valuable precursor or ligand in catalytic asymmetric reactions due to its chiral center.
• Agrochemical Development: Potential intermediate in the synthesis of novel active ingredients for crop protection.
• Material Science: Exploration of its use in the synthesis of specialty polymers or organic electronic materials.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies and novel heterocycle chemistry.

Basic Information

Product Name	Piperidin-4-Yl(2-Thienyl)Methanol
CAS No.	938458-94-7
Molecular Formula	C10H15NOS
Molecular Weight	197.30 g/mol
Synonyms	(2-Thienyl)(4-piperidinyl)methanol; 4-Piperidinyl(2-thienyl)methanol; α-(2-Thienyl)-4-piperidinemethanol; 1-(Hydroxy(2-thienyl)methyl)piperidin-4-ol (tautomeric form); 4-[(2-Thiophenyl)hydroxymethyl]piperidine; (Piperidin-4-yl)(thiophen-2-yl)methanol; 938458-94-7; (2-Thienyl)-(4-piperidinyl)-methanol
EINECS	Contact for details

Quality Control

Our Piperidin-4-Yl(2-Thienyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) with full specifications and chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.