Description

(αr,2R)-α-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Hydroxyimino)Acetyl]Amino]-4-Carboxy-5-Ethenyl-3,6-Dihydro-2H-1,3-Thiazine-2-Acetic Acid is a sophisticated, high-purity chemical building block with a complex heterocyclic structure. This compound is of significant value in advanced pharmaceutical research and development, particularly as a key intermediate in the synthesis of novel β-lactam antibiotics and other biologically active molecules. It is primarily sought after by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of next-generation anti-infective agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced cephalosporin and penem class antibiotics.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities targeting bacterial infections.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex molecules with thiazine and thiazole rings in custom synthesis projects.
• Bioconjugation: Potential use in developing antibody-drug conjugates (ADCs) or other targeted therapies due to its reactive carboxylic acid and amino groups.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(αr,2R)-α-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Hydroxyimino)Acetyl]Amino]-4-Carboxy-5-Ethenyl-3,6-Dihydro-2H-1,3-Thiazine-2-Acetic Acid
CAS No.	937819-42-6
Molecular Formula	C16H17N5O7S2
Molecular Weight	463.47 g/mol
Synonyms	(2R,4R)-2-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(hydroxyimino)acetyl]amino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic acid; (Ar,2R)-α-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(hydroxyimino)acetyl]amino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic acid; 4-Carboxy-5-ethenyl-2-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-3,6-dihydro-2H-1,3-thiazine-2-acetic acid; Advanced Cephalosporin Intermediate; β-Lactam Synthon; Thiazine-Thiazole Derivative
EINECS	Contact for details

Quality Control

Our production of (αr,2R)-α-[[(2Z)-2-(2-Amino-4-Thiazolyl)-2-(Hydroxyimino)Acetyl]Amino]-4-Carboxy-5-Ethenyl-3,6-Dihydro-2H-1,3-Thiazine-2-Acetic Acid adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting research-grade and pharmaceutical intermediate standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.