Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-1-[(1,1-Dimethylethyl)Dimethylsilyl]- is a high-purity, protected heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core structure.
• Material Science: Serves as a precursor for creating specialized organic electronic materials and functional polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for commercial production.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-1-[(1,1-Dimethylethyl)Dimethylsilyl]-
CAS No.	937796-62-8
Molecular Formula	C13H19ClN2Si
Molecular Weight	266.84 g/mol
Synonyms	4-Chloro-1-[(1,1-dimethylethyl)dimethylsilyl]-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-1-(tert-butyldimethylsilyl)-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-1-TBDMS-7-azaindole; 4-Chloro-1-((tert-butyldimethylsilyl))-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-1-[(1,1-dimethylethyl)dimethylsilyl]-; 4-Chloro-1-(tert-butyldimethylsilyl)-7-azaindole; TBDMS-4-chloro-7-azaindole; 4-Cl-1-TBDMS-7-AZA
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-1-[(1,1-Dimethylethyl)Dimethylsilyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.