Description

4'-(3-Bromothien-2-Yl)Acetophenone is a high-purity brominated aromatic ketone building block, essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and materials science research. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, leveraging the thiophene and bromine motifs for bioactivity.
• Organic Electronic Materials: Serves as a building block for π-conjugated systems in the research of organic semiconductors, OLEDs, and photovoltaic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	4'-(3-Bromothien-2-Yl)Acetophenone
CAS No.	937796-01-5
Molecular Formula	C12H9BrOS
Molecular Weight	281.17 g/mol
Synonyms	1-[4-(3-Bromothiophen-2-yl)phenyl]ethanone; 4-(3-Bromothien-2-yl)acetophenone; 4'-Acetyl-3'-bromo-2,2'-bithiophene (related); 4-(3-Bromothiophen-2-yl)acetophenone; 3-Bromo-2-(4-acetylphenyl)thiophene; p-(3-Bromothien-2-yl)acetophenone; 1-(4-(3-Bromothiophen-2-yl)phenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 4'-(3-Bromothien-2-Yl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.