Description

7-Bromo-1-Ethyl-5-Methyl-1H-Indole-2,3-Dione (Saltdata: Free) is a high-purity, functionalized isatin derivative, a crucial building block in advanced organic synthesis. Its value lies in providing a versatile, brominated scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and fine chemical manufacturing. The compound is supplied as a free base, offering maximum flexibility for downstream synthetic transformations.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Organic Synthesis Building Block: The bromine atom and carbonyl groups provide handles for cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions.
• Material Science: A potential monomer or precursor for creating functional polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized in creating molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in medicinal chemistry and methodology development.

Basic Information

Product Name	7-Bromo-1-Ethyl-5-Methyl-1H-Indole-2,3-Dione (Saltdata: Free)
CAS No.	937664-94-3
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	7-Bromo-1-ethyl-5-methylindoline-2,3-dione; 1-Ethyl-7-bromo-5-methyl-1H-indole-2,3-dione; 7-Bromo-1-ethyl-5-methylisatin; 1-Ethyl-7-bromo-5-methylisatin; 5-Methyl-7-bromo-1-ethylisatin; Isatin, 7-bromo-1-ethyl-5-methyl-; 937664-94-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 7-Bromo-1-Ethyl-5-Methyl-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP (current Good Manufacturing Practice) principles and ISO-guided processes guarantees a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.