Description

Acetamide, n-[3-(Hydroxymethyl)-4-Methyl-2-Thienyl]- is a specialized heterocyclic acetamide derivative featuring a thiophene core, serving as a critical synthetic intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme interactions or as a scaffold for probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Acetamide, n-[3-(Hydroxymethyl)-4-Methyl-2-Thienyl]-
CAS No.	937645-00-6
Molecular Formula	C9H11NO2S
Molecular Weight	197.25 g/mol
Synonyms	N-[3-(Hydroxymethyl)-4-methylthiophen-2-yl]acetamide; 2-Acetamido-4-methyl-5-(hydroxymethyl)thiophene; 4-Methyl-5-(hydroxymethyl)thiophene-2-acetamide; Acetamide, N-(3-(hydroxymethyl)-4-methyl-2-thienyl)-; 937645-00-6; Thiophene acetamide derivative
EINECS	Contact for details

Quality Control

Every batch of Acetamide, n-[3-(Hydroxymethyl)-4-Methyl-2-Thienyl]- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development work. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.