Description

5-Chloro-2-(2,3-Dihydro-1H-Indol-1-Yl)Aniline is a high-value, functionalized aniline derivative featuring an indoline moiety, making it a versatile building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on heterocyclic chemistry, medicinal chemistry, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its indoline scaffold.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of specialty polymers, dyes, and photoactive materials.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including C-N coupling reactions and heterocycle functionalization.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to create diverse compound libraries for biological evaluation.

Basic Information

Product Name	5-Chloro-2-(2,3-Dihydro-1H-Indol-1-Yl)Aniline
CAS No.	937606-11-6
Molecular Formula	C14H13ClN2
Molecular Weight	244.72 g/mol
Synonyms	1-(5-Chloro-2-aminophenyl)indoline; 5-Chloro-2-(2,3-dihydro-1H-indol-1-yl)benzenamine; 5-Chloro-N-(2,3-dihydro-1H-indol-1-yl)aniline; 1-(2-Amino-4-chlorophenyl)indoline; Benzenamine, 5-chloro-2-(2,3-dihydro-1H-indol-1-yl)-; 937606-11-6
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(2,3-Dihydro-1H-Indol-1-Yl)Aniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.