Description

1-(tert-Butyl) 2-Ethyl 5-Bromo-1H-Indole-1,2-Dicarboxylate is a high-purity, synthetically valuable brominated indole derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block for the development of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds and functionalized indole derivatives in medicinal chemistry.
• Material Science: Potential monomer or precursor for the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	1-(tert-Butyl) 2-Ethyl 5-Bromo-1H-Indole-1,2-Dicarboxylate
CAS No.	937602-51-2
Molecular Formula	C₁₇H₂₀BrNO₄
Molecular Weight	382.25 g/mol
Synonyms	5-Bromo-1H-indole-1,2-dicarboxylic acid 1-(1,1-dimethylethyl) 2-ethyl ester; 1-tert-Butyl 2-ethyl 5-bromoindole-1,2-dicarboxylate; 5-Bromo-1-(tert-butoxycarbonyl)-2-(ethoxycarbonyl)indole; 5-Bromo-2-ethoxycarbonyl-1-N-Boc-indole; 1-Boc-2-COOEt-5-Br-indole; 5-Br-1-N-Boc-indole-2-carboxylic acid ethyl ester; Ethyl 5-bromo-1-[(tert-butoxy)carbonyl]-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1-(tert-Butyl) 2-Ethyl 5-Bromo-1H-Indole-1,2-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and structural identity, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.