Description

2-[(Tetrahydrofuran-2-Ylmethyl)Amino]-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylic Acid is a high-value, multifunctional heterocyclic building block featuring a thiazole core with a trifluoromethyl group and a tetrahydrofuran-derived amine side chain. This compound is critical for medicinal chemistry and agrochemical research, where its unique structure enables the synthesis of novel bioactive molecules with enhanced metabolic stability and binding affinity. It is primarily sought by R&D and process development teams in the pharmaceutical, agrochemical, and advanced material sectors for creating new active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory therapeutic areas.
• Agrochemical Active Ingredient Precursor: Used in the research and synthesis of next-generation herbicides, fungicides, and insecticides leveraging the bioactivity of the thiazole and trifluoromethyl motifs.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-[(Tetrahydrofuran-2-Ylmethyl)Amino]-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylic Acid
CAS No.	937597-53-0
Molecular Formula	C11H13F3N2O3S
Molecular Weight	310.29 g/mol
Synonyms	4-(Trifluoromethyl)-2-[[(tetrahydro-2-furanyl)methyl]amino]-5-thiazolecarboxylic acid; 2-[(Tetrahydrofuran-2-ylmethyl)amino]-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid; 5-Thiazolecarboxylic acid, 2-[[(tetrahydro-2-furanyl)methyl]amino]-4-(trifluoromethyl)-; 937597-53-0; TFAT; THF-Thiazole-Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-[(Tetrahydrofuran-2-Ylmethyl)Amino]-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.