Description

1-(5-Chloro-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethanone is a high-purity, synthetically derived heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical scaffold to synthesize and explore new therapeutic agents targeting a range of central nervous system and other disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex heterocyclic compounds for agrochemical and material science applications.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.
• Academic Research: Employed in university and institutional labs for methodological development and the study of novel organic reactions.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Item	Detail
Product Name	1-(5-Chloro-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethanone
CAS No.	937591-81-6
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	2-Acetyl-5-chloro-1,2,3,4-tetrahydroisoquinoline; 5-Chloro-2-acetyl-1,2,3,4-tetrahydroisoquinoline; 1-(5-Chloro-3,4-dihydro-2(1H)-isoquinolinyl)ethanone; 5-Chloro-2-acetyl-1,2,3,4-tetrahydroisoquinoline; N-Acetyl-5-chloro-1,2,3,4-tetrahydroisoquinoline; 5-Chloro-1,2,3,4-tetrahydro-2-isoquinolyl methyl ketone; Ethanone, 1-(5-chloro-3,4-dihydro-2(1H)-isoquinolinyl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.