Description

1-(7-Bromo-3,4-dihydroisoquinolin-2(1H)-yl)ethanone is a high-purity brominated isoquinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and cardiovascular diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoquinoline core.
• Ligand and Catalyst Development: Acts as a precursor for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, fluorescent dyes, and photostabilizers due to its conjugated aromatic system.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.
• Custom Synthesis: A starting point for the contract manufacturing of proprietary compounds and bespoke chemical entities for client-specific projects.

Basic Information

Product Name	1-(7-Bromo-3,4-dihydroisoquinolin-2(1H)-yl)ethanone
CAS No.	937591-28-1
Molecular Formula	C11H12BrNO
Molecular Weight	254.12 g/mol
Synonyms	1-(7-Bromo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one; 2-Acetyl-7-bromo-1,2,3,4-tetrahydroisoquinoline; 7-Bromo-2-acetyl-1,2,3,4-tetrahydroisoquinoline; Ethanone, 1-(7-bromo-3,4-dihydro-2(1H)-isoquinolinyl)-; 1-(7-Bromo-3,4-dihydro-2H-isoquinolin-2-yl)ethanone; N-Acetyl-7-bromo-1,2,3,4-tetrahydroisoquinoline; 7-Bromo-N-acetyl-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 1-(7-Bromo-3,4-dihydroisoquinolin-2(1H)-yl)ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.