Description

(R)-tert-Butyl 2-(1H-Indol-3-Yl)-1-(4-(4-Methoxybenzyl)-5-Phenethyl-4H-1,2,4-Triazol-3-Yl)Ethylcarbamate is a sophisticated chiral intermediate featuring a unique molecular architecture combining indole, triazole, and carbamate functional groups. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of targeted bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, drug-like scaffold.
• Process Chemistry Development: Serves as a critical intermediate for scaling up the production of active pharmaceutical ingredients (APIs) under current Good Manufacturing Practice (cGMP) standards.
• Asymmetric Synthesis: Employed in the development of novel synthetic routes that require high enantiomeric purity for biological testing.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in API manufacturing.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biological target identification and validation studies.

Basic Information

Item	Detail
Product Name	(R)-tert-Butyl 2-(1H-Indol-3-Yl)-1-(4-(4-Methoxybenzyl)-5-Phenethyl-4H-1,2,4-Triazol-3-Yl)Ethylcarbamate
CAS No.	937248-15-2
Molecular Formula	C33H37N5O3
Molecular Weight	551.68 g/mol
Synonyms	(R)-Boc-Protected Indole-Triazole Derivative; tert-Butyl (R)-2-(1H-indol-3-yl)-1-[4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-1,2,4-triazol-3-yl]ethylcarbamate; (R)-N-Boc-2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethanamine; 937248-15-2; CAS 937248-15-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D, with testing performed using validated methods such as HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.