Description

(3-(1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Phenyl)Boronic Acid Pinacol Ester is a high-value, protected boronic ester building block designed for advanced organic synthesis. This compound is critical for enabling efficient cross-coupling reactions, particularly in the construction of complex pharmaceutical intermediates. It is primarily utilized by medicinal chemists and process development scientists in the research and production of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester derivative, essential for constructing biaryl motifs in drug molecules.
• Pharmaceutical Intermediate Synthesis: Serves as a crucial building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research & Development: Used in the discovery and development of new herbicides, fungicides, and insecticides that require complex aromatic structures.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors and light-emitting materials for electronic displays.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis to create diverse compound libraries for biological screening.
• Process Chemistry & Scale-up: Provides a stable and handleable boronate source for optimizing and scaling up manufacturing routes for commercial APIs.

Basic Information

Product Name	(3-(1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Phenyl)Boronic Acid Pinacol Ester
CAS No.	937048-47-0
Molecular Formula	C22H34BNO4
Molecular Weight	387.33 g/mol
Synonyms	Boc-4-(3-Boronophenyl)piperidine Pinacol Ester; 3-(1-Boc-piperidin-4-yl)benzeneboronic Acid Pinacol Ester; 3-(1-(tert-Butoxycarbonyl)-4-piperidinyl)benzeneboronic Acid Pinacol Ester; 3-(N-Boc-4-piperidinyl)phenylboronic Acid Pinacol Ester; 1-Boc-4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl))phenyl)piperidine; tert-Butyl 4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (3-(1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Phenyl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. The product is light-sensitive (store away from light). Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.