Description

4-[4-(Trifluoromethyl)Phenyl]Thiazole-2-Thiol is a high-purity, specialized organic intermediate featuring a thiazole core substituted with a thiol group and a trifluoromethylphenyl moiety. This compound is valued for its unique electronic properties and structural motif, which are critical for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific heterocyclic architecture.

Basic Information

Product Name	4-[4-(Trifluoromethyl)Phenyl]Thiazole-2-Thiol
CAS No.	936850-88-3
Molecular Formula	C10H6F3NS2
Molecular Weight	261.28 g/mol
Synonyms	2-Mercapto-4-[4-(trifluoromethyl)phenyl]thiazole; 4-(4-Trifluoromethylphenyl)-2-thiazolethiol; 2-Thiazolethiol, 4-[4-(trifluoromethyl)phenyl]-; 4-(α,α,α-Trifluoro-p-tolyl)-2-mercaptothiazole; 2-Mercapto-4-(4-trifluoromethylphenyl)thiazole; 4-(4-Trifluoromethylphenyl)-1,3-thiazole-2-thiol; 936850-88-3
EINECS	Contact for details

Quality Control

Our 4-[4-(Trifluoromethyl)Phenyl]Thiazole-2-Thiol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.