Description

2-(4-Bromophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is a versatile brominated aromatic diol building block with significant synthetic utility. Its molecular structure, featuring a central tertiary carbon bearing hydroxymethyl groups and a 4-bromophenyl substituent, makes it a valuable intermediate for constructing complex molecules in advanced material and pharmaceutical research. This compound is particularly sought after by R&D chemists and process development scientists working in fine chemical synthesis. Its primary value lies in enabling the development of novel polymers, liquid crystals, and active pharmaceutical ingredients (APIs) through further functionalization.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon or building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Liquid Crystal Materials: Used in the synthesis of advanced liquid crystal monomers and polymers for display technologies, where the bromophenyl and diol groups contribute to molecular anisotropy and mesogenic properties.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polyesters, polyurethanes, and epoxy resins, enhancing material properties like thermal stability and mechanical strength.
• Organic Synthesis Building Block: Employed in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions, where the bromine atom serves as a handle for further aromatic functionalization.
• Agrochemical Research: Utilized as an intermediate in the design and synthesis of novel herbicides, fungicides, or plant growth regulators.
• Material Science Research: Investigated for creating novel organic frameworks, dendrimers, or other functional materials due to its multifunctional, rigid structure.

Basic Information

Product Name	2-(4-Bromophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol
CAS No.	936494-74-5
Molecular Formula	C11H15BrO3
Molecular Weight	275.14 g/mol
Synonyms	2-(4-Bromophenyl)-2-(hydroxymethyl)-1,3-propanediol; 1,3-Propanediol, 2-(4-bromophenyl)-2-(hydroxymethyl)-; 4-Bromo-α,α-bis(hydroxymethyl)benzenemethanol; 2-(p-Bromophenyl)-2-(hydroxymethyl)propane-1,3-diol; (4-Bromophenyl)bis(hydroxymethyl)methanol; p-Bromophenylbis(hydroxymethyl)methanol
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity assay and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We can support development projects with custom purity grades and specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product quality and stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.