Description

n-(3-Dimethylamino-Propyl)-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is a high-purity, advanced pharmaceutical intermediate featuring a boronic ester pinacol group. This compound matters as a critical building block in modern synthetic chemistry, enabling key carbon-carbon bond formation reactions essential for constructing complex molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for oncology and other targeted therapies.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex drug candidates, especially kinase inhibitors.
• Organic Synthesis Research: Used in academic and industrial R&D for developing new synthetic methodologies and novel organic compounds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	n-(3-Dimethylamino-Propyl)-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide
CAS No.	936250-16-7
Molecular Formula	C18H29BN2O3
Molecular Weight	332.25 g/mol
Synonyms	3-((3-(Dimethylamino)propyl)carbamoyl)phenylboronic acid pinacol ester; N-[3-(Dimethylamino)propyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[3-(dimethylamino)propyl]benzamide; Benzamide, N-[3-(dimethylamino)propyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 936250-16-7; 3-Boronic acid, N-[3-(dimethylamino)propyl]benzamide, pinacol ester
EINECS	Contact for details

Quality Control

Our n-(3-Dimethylamino-Propyl)-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.