Description

(S)-Isoquinoline-5-Sulfonic Acid Pyrrolidin-3-Ylamide Dihydrochloride is a high-purity, chiral organic compound primarily utilized as a sophisticated building block in pharmaceutical research and development. Its value lies in its specific stereochemistry and functional groups, which make it a critical intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and bioactive molecules. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who are focused on creating new therapeutic agents, particularly in areas requiring precise molecular recognition.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API synthesis routes.
• Biochemical Probe Development: Can be utilized to create tool compounds for studying biological pathways and enzyme functions.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals for advanced applications.

Basic Information

Product Name	(S)-Isoquinoline-5-Sulfonic Acid Pyrrolidin-3-Ylamide Dihydrochloride
CAS No.	936233-15-7
Molecular Formula	C₁₃H₁₇N₃O₂S • 2HCl
Molecular Weight	368.28 g/mol (free base: 279.36 g/mol)
Synonyms	(S)-5-(Pyrrolidin-3-ylcarbamoyl)isoquinoline-8-sulfonic acid dihydrochloride; (S)-Isoquinoline-8-sulfonic acid, 5-[(3-pyrrolidinylamino)carbonyl]-, dihydrochloride; (S)-5-[(3-Aminopyrrolidin-1-yl)carbonyl]isoquinoline-8-sulfonic acid dihydrochloride; (S)-8-Sulfo-5-[(3-pyrrolidinylamino)carbonyl]isoquinoline dihydrochloride; Pyrrolidin-3-Ylamide Dihydrochloride of (S)-Isoquinoline-5-Sulfonic Acid; CAS 936233-15-7
EINECS	Contact for details

Quality Control

Our (S)-Isoquinoline-5-Sulfonic Acid Pyrrolidin-3-Ylamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications, including chiral purity and impurity profiles, are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.