Description

(S)-Isoquinoline-5-Sulfonic Acid Piperidin-3-Ylamide Dihydrochloride CAS NO 936233-07-7 is a high-purity, chiral small molecule building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its specific stereochemistry and functional groups, which make it a critical intermediate for synthesizing novel, targeted therapeutic agents. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors who are developing new drug candidates, particularly in areas requiring precise molecular recognition.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) with specific stereochemical requirements.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Protease Inhibitor Development: Serves as a potential scaffold or precursor in the design of inhibitors for various protease enzymes.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and target validation.
• Asymmetric Synthesis: Employed as a starting material or intermediate in asymmetric catalytic reactions to introduce chiral centers.
• Preclinical Drug Development: Integral to the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology studies.

Basic Information

Product Name	(S)-Isoquinoline-5-Sulfonic Acid Piperidin-3-Ylamide Dihydrochloride
CAS No.	936233-07-7
Molecular Formula	C18H20N4O2S · 2HCl
Molecular Weight	429.36 g/mol (Free base: 356.44 g/mol)
Synonyms	(S)-5-(3-Piperidinylsulfamoyl)isoquinoline dihydrochloride; (S)-Piperidin-3-yl isoquinoline-5-sulfonamide dihydrochloride; (S)-N-(Piperidin-3-yl)isoquinoline-5-sulfonamide dihydrochloride; UNII-6F4V8A2T0F; 936233-07-7; (S)-ISOQUINOLINE-5-SULFONIC ACID PIPERIDIN-3-YLAMIDE DIHYDROCHLORIDE; 6F4V8A2T0F
EINECS	Contact for details

Quality Control

Our (S)-Isoquinoline-5-Sulfonic Acid Piperidin-3-Ylamide Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to industry-standard analytical protocols, including HPLC, NMR, and chiral analysis, to guarantee the integrity of the stereochemical center and overall chemical purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.