Description

(S)-5-(3-Benzyl-Piperazine-1-Sulfonyl)-Isoquinoline Dihydrochloride CAS NO 936233-03-3 is a high-purity, chiral organic compound belonging to the class of sulfonylated piperazine-isoquinoline derivatives. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents targeting central nervous system disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe: Employed in the development of tool compounds to study biological pathways and protein-ligand interactions.
• Process Chemistry Development: Serves as a starting material for optimizing synthetic routes and scaling up production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodological studies.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(S)-5-(3-Benzyl-Piperazine-1-Sulfonyl)-Isoquinoline Dihydrochloride
CAS No.	936233-03-3
Molecular Formula	C20H22N4O2S • 2HCl
Molecular Weight	467.85 g/mol (free base: 382.48 g/mol)
Synonyms	(S)-5-[(3-Benzylpiperazin-1-yl)sulfonyl]isoquinoline dihydrochloride; (S)-5-(3-Benzyl-1-piperazinylsulfonyl)isoquinoline dihydrochloride; (S)-5-(3-Benzylpiperazine-1-sulfonyl)isoquinoline hydrochloride (1:2); UNII-2Q7K5J6V8I; 936233-03-3; (S)-5-(3-Benzylpiperazinylsulfonyl)isoquinoline 2HCl
EINECS	Contact for details

Quality Control

Our (S)-5-(3-Benzyl-Piperazine-1-Sulfonyl)-Isoquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.