Description

Boronic Acid, B-(2,3-Dihydro-1H-Indol-5-Yl)- is a specialized organoboron compound featuring an indoline scaffold, making it a valuable synthetic intermediate. Its primary commercial value lies in its role as a key building block in modern cross-coupling reactions, such as the Suzuki-Miyaura reaction, for constructing complex molecules. This high-purity reagent is essential for research and development in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, due to its indoline core.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring complex heterocyclic structures.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, including OLEDs and sensors.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in bioconjugation and activity-based protein profiling (ABPP) studies.
• Catalyst & Ligand Development: Utilized to create novel boron-containing ligands for asymmetric catalysis and transition metal complexes.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	Boronic Acid, B-(2,3-Dihydro-1H-Indol-5-Yl)-
CAS No.	935853-24-0
Molecular Formula	C8H10BNO2
Molecular Weight	162.98 g/mol
Synonyms	(2,3-Dihydro-1H-indol-5-yl)boronic acid; 5-Indolineboronic acid; 1H-Indole-5-boronic acid, 2,3-dihydro-; 5-Boronoindoline; B-(2,3-Dihydroindol-5-yl)boronic acid; 2,3-Dihydro-1H-indole-5-boronic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-(2,3-Dihydro-1H-Indol-5-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container should be opened only under controlled, moisture-free conditions and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.