Description

(Z)-4-((E)-1-(3,3-Dimethyl-4-Oxo-1-p-Tolylazetidin-2-Yl)-5-Methoxy-3-(4-Methoxyphenylimino)Indolin-2-Ylidene)-3,3-Dimethyl-1-p-Tolylazetidin-2-One is a high-purity, complex heterocyclic compound featuring a unique indolin-2-one and azetidin-2-one fused structure. This compound serves as a critical advanced intermediate in the synthesis of novel pharmaceutical agents, particularly in the development of targeted therapies. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the discovery and production of next-generation drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for oncology and other therapeutic areas.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probe: Serves as a core structure for developing molecular probes to study biological pathways and protein interactions.
• Process Chemistry: Employed in route scouting and scale-up studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value compounds for clinical trials.

Basic Information

Item	Details
Product Name	(Z)-4-((E)-1-(3,3-Dimethyl-4-Oxo-1-p-Tolylazetidin-2-Yl)-5-Methoxy-3-(4-Methoxyphenylimino)Indolin-2-Ylidene)-3,3-Dimethyl-1-p-Tolylazetidin-2-One
CAS No.	935756-05-1
Molecular Formula	C39H38N4O4
Molecular Weight	626.75 g/mol
Synonyms	4-[(1Z)-1-[(2E)-2-[(4-Methoxyphenyl)imino]-5-methoxy-3H-indol-2-ylidene]-2-(4-methylphenyl)-4-oxo-3-azetidinyl]-2,2-dimethyl-1-(4-methylphenyl)-3-azetidinone; (Z)-4-((E)-1-(3,3-Dimethyl-4-oxo-1-p-tolylazetidin-2-yl)-5-methoxy-3-(4-methoxyphenylimino)indolin-2-ylidene)-3,3-dimethyl-1-p-tolylazetidin-2-one; 935756-05-1; Azetidinone-indole hybrid intermediate; Complex spiro-fused heterocycle
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Identity and purity are confirmed via advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.