Description

4-Amino-5-Chloro-1-Benzofuran-7-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique fused-ring structure, featuring both amino and carboxylic acid functional groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzofuran-based drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with tailored optical or electronic properties.
• Organic Synthesis Building Block: Employed in medicinal chemistry for parallel synthesis and library generation due to its reactive amine and acid groups.
• Dye & Pigment Intermediate: Utilized in the production of advanced colorants and fluorescent markers.
• Academic & R&D: A valuable reagent for methodological studies and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	4-Amino-5-Chloro-1-Benzofuran-7-Carboxylic Acid
CAS No.	935696-96-1
Molecular Formula	C9H6ClNO3
Molecular Weight	211.60 g/mol
Synonyms	4-Amino-5-chloro-7-carboxybenzofuran; 5-Chloro-4-aminobenzofuran-7-carboxylic acid; 7-Carboxy-4-amino-5-chlorobenzofuran; 1-Benzofuran-7-carboxylic acid, 4-amino-5-chloro-; 4-Amino-5-chloro-1-benzofuran-7-carboxylate; 935696-96-1; 4-Amino-5-chlorobenzofuran-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-1-Benzofuran-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.