Description

(1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanamine Hydrochloride CAS NO 935466-77-6 is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its fused pyrrolopyridine scaffold, which is a privileged structure in medicinal chemistry for designing novel bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on kinase inhibitor discovery and other targeted therapeutic programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors targeting various oncology and inflammatory pathways.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound Development: Employed in the creation of probes and labeled compounds for investigating biological mechanisms and target engagement.
• Agrochemical Research: Potential application in the development of new active ingredients with specific biological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanamine Hydrochloride
CAS No.	935466-77-6
Molecular Formula	C8H10ClN3
Molecular Weight	183.64 g/mol
Synonyms	4-(Aminomethyl)-1H-pyrrolo[2,3-b]pyridine hydrochloride; 1H-Pyrrolo[2,3-b]pyridine-4-methanamine hydrochloride; 4-(Aminomethyl)-7-azaindole hydrochloride; 7-Azaindole-4-methanamine hydrochloride; (1H-Pyrrolo[2,3-b]pyridin-4-yl)methanamine HCl; 4-Aminomethyl-7-azaindole hydrochloride; 4-Carbinamine-7-azaindole hydrochloride
EINECS	Contact for details

Quality Control

Our (1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring material of research and pharmaceutical grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.