Description

4-Chloro-6-Cyano-7-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused ring structure, featuring chloro, cyano, and nitrogen-rich azaindole motifs, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging its halogen and nitrile groups for further functionalization.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of organic electronic materials, such as OLED emitters and charge transport layers.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Academic & Contract Research: A versatile starting material for methodological studies in heterocyclic and medicinal chemistry within universities and CROs.

Basic Information

Product Name	4-Chloro-6-Cyano-7-Azaindole
CAS No.	935466-70-9
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	7-Azaindole-4-carbonitrile, 6-chloro-; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 4-Chloro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 6-Chloro-4-cyano-7-azaindole; 4-Chloro-6-cyano-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 6-chloro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Cyano-7-Azaindole is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data. Our quality systems are designed to support regulatory filings, adhering to cGMP principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.