Description

3-Thiophenamine, Tetrahydro-, 1,1-Dioxide, Hydrochloride (1:1), (3R)- is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific stereochemistry and functional groups are critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3-Thiophenamine, Tetrahydro-, 1,1-Dioxide, Hydrochloride (1:1), (3R)-
CAS No.	935455-27-9
Molecular Formula	C4H10ClNO2S
Molecular Weight	171.65 g/mol
Synonyms	(R)-3-Aminotetrahydrothiophene 1,1-Dioxide Hydrochloride; (3R)-3-Aminotetrahydrothiophene-1,1-dioxide hydrochloride; (R)-Tetrahydro-3-thiophenamine 1,1-Dioxide Hydrochloride; (R)-3-Aminothiolane 1,1-Dioxide Hydrochloride; (R)-Aminosulfolane Hydrochloride; (R)-3-Aminosulfolane HCl; (R)-3-Aminothiolane-1,1-dioxide HCl; (R)-3-Aminotetrahydrothiophene-1,1-dioxide HCl salt
EINECS	Contact for details

Quality Control

Our 3-Thiophenamine, Tetrahydro-, 1,1-Dioxide, Hydrochloride (1:1), (3R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process development use. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.