Description

(E)-1-(4-(2-Methyl-10H-Benzo[B]Thieno[2,3-E][1,4]Diazepin-4-Yl)Piperazin-1-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate of significant interest in medicinal chemistry research and development. This compound is valued for its role as a key synthetic building block in the creation of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacology domains. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel benzothienodiazepine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with targeted biological activity.
• CNS Drug Development: Serves as a core scaffold for research into potential treatments for neurological and psychiatric disorders.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Chemistry: Used in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(E)-1-(4-(2-Methyl-10H-Benzo[B]Thieno[2,3-E][1,4]Diazepin-4-Yl)Piperazin-1-Yl)Ethanone
CAS No.	935272-10-9
Molecular Formula	C18H20N4OS
Molecular Weight	340.44 g/mol
Synonyms	1-[4-(2-Methylbenzo[4,5]thieno[3,2-f][1,4]diazepin-4-yl)piperazin-1-yl]ethan-1-one; (E)-1-(4-(2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazin-1-yl)ethanone; 2-Methyl-4-(4-acetylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine; Acetylated Benzothienodiazepine Piperazine Derivative; BTDZ Intermediate; CAS 935272-10-9
EINECS	Contact for details

Quality Control

Our (E)-1-(4-(2-Methyl-10H-Benzo[B]Thieno[2,3-E][1,4]Diazepin-4-Yl)Piperazin-1-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.