Description

6-Chloro-2-Trifluoromethylindole is a high-purity, multi-functional indole derivative characterized by its unique halogenated and trifluoromethylated structure. This compound serves as a critical advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research and development. It is essential for medicinal chemists and process development scientists working on novel active ingredients, offering a versatile scaffold for further functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging the biological activity of the indole core.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Chloro-2-Trifluoromethylindole
CAS No.	934843-27-3
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	2-(Trifluoromethyl)-6-chloro-1H-indole; 6-Chloro-2-(trifluoromethyl)-1H-indole; 6-Chloro-2-trifluoromethyl-1H-indole; 1H-Indole, 6-chloro-2-(trifluoromethyl)-; 934843-27-3
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Trifluoromethylindole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.