Description

4-Iodo-1-Methyl-1H-Indole is a versatile halogenated indole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the iodine atom, which provides an excellent handle for further functionalization via cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting serotonin receptor modulators and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate the indole scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where halogenated aromatics are essential.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	4-Iodo-1-Methyl-1H-Indole
CAS No.	934767-42-7
Molecular Formula	C9H8IN
Molecular Weight	257.07 g/mol
Synonyms	1-Methyl-4-iodo-1H-indole; 4-Iodo-1-methylindole; 1-Methyl-4-iodindole; 4-Iodo-1-methyl-1H-indole; 934767-42-7; 4-Iodo-1-methylindole; 1-Methyl-4-iodoindole
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Methyl-1H-Indole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or using amber glassware when possible.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.