Description

1-(4-Bromophenoxymethyl)-2-Fluorobenzene is a specialized fluorinated and brominated aromatic ether, serving as a high-value intermediate in advanced organic synthesis. Its unique bifunctional structure, featuring both a bromo and a fluoro substituent on distinct aromatic rings, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce specific halogenated motifs into lead compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Polymer Science: Employed in the creation of specialty polymers and high-performance resins, where its halogenated structure can impart flame retardancy or modify polymer chain properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira), enabling rapid diversification of molecular scaffolds.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry teams exploring structure-activity relationships (SAR) and scalable synthetic routes.

Basic Information

Product Name	1-(4-Bromophenoxymethyl)-2-Fluorobenzene
CAS No.	934240-59-2
Molecular Formula	C₁₃H₁₀BrFO
Molecular Weight	281.12 g/mol
Synonyms	2-Fluoro-1-[(4-bromophenoxy)methyl]benzene; 1-[(4-Bromophenoxy)methyl]-2-fluorobenzene; 2-Fluorobenzyl 4-bromophenyl ether; 4-Bromophenyl 2-fluorobenzyl ether; (2-Fluorobenzyl)(4-bromophenyl) ether; 4-Bromo-α-(2-fluorophenyl)phenol methyl ether; Benzene, 1-(4-bromophenoxymethyl)-2-fluoro-
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromophenoxymethyl)-2-Fluorobenzene adheres to stringent quality management protocols. Every batch is characterized and purified to meet the exacting standards required for advanced synthetic applications. Comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, is performed to ensure identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.