Description

1,5-Diazabicyclo[4.3.0]Non-5-Ene (DBN) is a highly versatile bicyclic amidine base, widely recognized for its exceptional utility in organic synthesis. Its strong, non-nucleophilic basicity makes it a critical reagent for facilitating challenging deprotonations and catalyzing complex condensation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where precise control over reaction pathways is paramount.

Application

• Pharmaceutical Synthesis: As a catalyst and base in the production of active pharmaceutical ingredients (APIs), particularly for complex heterocyclic compounds.
• Polymer Chemistry: Used as a catalyst for the synthesis of polyurethanes and other polymers, controlling polymerization rates and molecular weight.
• Agrochemical Manufacturing: Employed in the synthesis of advanced pesticides and herbicides, where its strong base properties are required for key cyclization and alkylation steps.
• Organic Synthesis Reagent: A superior base for deprotonation of weak carbon acids, enolate formation, and elimination reactions under mild conditions.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D labs for developing new synthetic methodologies and exploring reaction mechanisms.
• Fine Chemical Production: Facilitates the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	1,5-Diazabicyclo[4.3.0]Non-5-Ene
CAS No.	3001-72-7
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	DBN; 2,3,4,6,7,8-Hexahydro-1H-pyrimido[1,2-a]pyrimidine; 1,5-Diazabicyclo[4.3.0]non-5-ene; 1,5-Diazabicyclo[4.3.0]nonene; Amidino base DBN
EINECS	221-088-3

Quality Control

Our 1,5-Diazabicyclo[4.3.0]Non-5-Ene is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including GC, HPLC, and NMR, to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, physical properties, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.518 - 1.522
Density (g/mL, 20°C)	1.005 - 1.025

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.