Description

Phosphoramidochloridothioic Acid, n-Acetyl-, o-Methyl Ester is a specialized organophosphorus compound with a unique thiophosphoryl chloride core. This chemical is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecules in advanced research and development. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where phosphorus-containing motifs are critical.
• Agrochemical Research: Used in the development of next-generation pesticides, herbicides, and plant growth regulators that require specific thiophosphoryl functionalities.
• Chemical Synthesis: Serves as a pivotal reagent for introducing phosphoramidothioate groups into complex organic molecules, facilitating structure-activity relationship (SAR) studies.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for metal catalysis or as a precursor for functional materials science applications.
• Peptide & Nucleotide Chemistry: Potential use in the modification of biomolecules or in the synthesis of nucleotide analogs for biochemical research.

Basic Information

Product Name	Phosphoramidochloridothioic Acid, n-Acetyl-, o-Methyl Ester
CAS No.	934176-28-0
Molecular Formula	C3H7ClNO2PS
Molecular Weight	187.58 g/mol
Synonyms	O-Methyl N-acetylphosphoramidochloridothioate; Acetamide, N-[(chlorothiophosphinyl)oxy]-, methyl ester; Methyl N-acetylphosphoramidochloridothioate; N-Acetylphosphoramidochloridothioic Acid O-Methyl Ester; Phosphoramidochloridothioic acid, acetyl-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Phosphoramidochloridothioic Acid, n-Acetyl-, o-Methyl Ester is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.