Description

tert-Butyl (1-Methyl-1H-Indol-3-Yl)Carbamate is a protected indole derivative, a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Peptidomimetics & PROTACs: Serves as a protected amine component in the design of peptide mimics and proteolysis-targeting chimeras (PROTACs).
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Academic Research: A versatile reagent for methodological studies in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl (1-Methyl-1H-Indol-3-Yl)Carbamate
CAS No.	933800-38-5
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	1-Methyl-1H-indol-3-yl-carbamic acid tert-butyl ester; tert-Butyl N-(1-methyl-1H-indol-3-yl)carbamate; 3-[(tert-Butoxycarbonyl)amino]-1-methyl-1H-indole; 1-Methylindol-3-yl tert-butylcarbamate; Boc-1-Methyl-3-aminoindole; N-Boc-1-Methyl-3-aminoindole; N-(tert-Butoxycarbonyl)-1-methyl-1H-indol-3-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-Methyl-1H-Indol-3-Yl)Carbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.