Description

3H-Indol-3-One, 2-[(4-Fluoro-1H-Pyrrol-2-Yl)Methylene]-1,2-Dihydro- is a specialized heterocyclic organic compound featuring a unique indolone core fused with a fluorinated pyrrole moiety. This molecular architecture makes it a valuable high-purity building block for advanced research and development in medicinal chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical synthesis specialists for constructing novel molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Agrochemical Development: Potential application as an intermediate for creating new active ingredients with specific biological activity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce its distinct fluorinated heterocyclic structure into target molecules.
• Material Science Research: Investigated for its potential use in the development of organic semiconductors or specialty polymers due to its conjugated system.
• Biochemical Probe Development: Can be utilized to create labeled compounds or probes for studying biological mechanisms and pathways.

Basic Information

Product Name	3H-Indol-3-One, 2-[(4-Fluoro-1H-Pyrrol-2-Yl)Methylene]-1,2-Dihydro-
CAS No.	933782-85-5
Molecular Formula	C₁₃H₉FN₂O
Molecular Weight	228.23 g/mol
Synonyms	2-[(4-Fluoro-1H-pyrrol-2-yl)methylene]-1,2-dihydro-3H-indol-3-one; (Z)-2-((4-Fluoro-1H-pyrrol-2-yl)methylene)-2,3-dihydro-1H-indol-3-one; 4-Fluoro-2-((3-oxo-2,3-dihydro-1H-indol-2-ylidene)methyl)-1H-pyrrole; Fluorinated Indolone-Pyrrole Hybrid; 933782-85-5; AI3-71097; ZINC000012773756
EINECS	Contact for details

Quality Control

We supply this compound as a high-purity research-grade material. Every batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/LC-MS for structural confirmation, to ensure identity and consistency. Our quality system is designed to meet the stringent requirements of GMP/GLP environments where applicable. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.