Description

1,2,3,4-Tetrahydroisoquinoline-8-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. Its unique fused ring structure makes it a critical precursor for the development of novel pharmaceutical compounds and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Organic Synthesis Reagent: Used as a versatile precursor for constructing complex heterocyclic frameworks and fused ring systems in medicinal chemistry.
• Agrochemical Research: Serves as a starting material for developing novel pesticides and herbicides with specific biological activity.
• Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts for asymmetric synthesis applications.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and functional materials.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline-8-Carboxylic Acid
CAS No.	933753-84-5
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	8-Carboxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-8-isoquinolinecarboxylic Acid; THIQ-8-COOH; 1,2,3,4-Tetrahydroisoquinoline-8-carboxylic acid; 8-(Carboxy)-1,2,3,4-tetrahydroisoquinoline; Isoquinoline-8-carboxylic acid, 1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.