Description

1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its rigid, fused-ring structure which serves as a key scaffold in medicinal chemistry and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Medicinal Chemistry Scaffold: Serves as a privileged structure for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Acts as a building block for complex molecules, dyes, and advanced materials requiring a tetrahydroisoquinoline core.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in analytical method development.

Basic Information

Item	Details
Product Name	1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid
CAS No.	933752-32-0
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	6-Carboxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-isoquinolinecarboxylic Acid; THIQ-6-COOH; 1,2,3,4-Tetrahydroisoquinoline-6-carboxylic acid; 6-Carboxy-THIQ; 1,2,3,4-Tetrahydro-isoquinoline-6-carboxylic acid; 6-Carboxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.