Description

4-Thiazolecarboxylic Acid, 5-(Methylamino)- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole core enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate functionalized thiazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and organocatalysts due to its nitrogen and sulfur donor atoms.
• Material Science Research: Acts as a monomer or functional additive in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	4-Thiazolecarboxylic Acid, 5-(Methylamino)-
CAS No.	933751-45-2
Molecular Formula	C6H6N2O2S
Molecular Weight	170.19 g/mol
Synonyms	5-(Methylamino)-1,3-thiazole-4-carboxylic acid; 5-(Methylamino)thiazole-4-carboxylic acid; 4-Carboxy-5-(methylamino)thiazole; 5-Methylaminothiazole-4-carboxylic acid; Methylamino-thiazolecarboxylic acid; 933751-45-2; 5-(Methylamino)-4-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Thiazolecarboxylic Acid, 5-(Methylamino)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assay and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.