Description

1H-Indole-3-Carboxylic Acid, 5-Bromo-2-Chloro- is a halogenated indole derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the development of novel compounds with targeted biological activity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and receptor binding.
• Academic & Contract Research: Essential for synthetic methodology research and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid, 5-Bromo-2-Chloro-
CAS No.	933740-77-3
Molecular Formula	C9H5BrClNO2
Molecular Weight	274.50 g/mol
Synonyms	5-Bromo-2-chloro-1H-indole-3-carboxylic acid; 2-Chloro-5-bromoindole-3-carboxylic acid; 5-Bromo-2-chloroindole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 5-bromo-2-chloro-; 933740-77-3; 5-Br-2-Cl-indole-3-COOH
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-3-Carboxylic Acid, 5-Bromo-2-Chloro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.