Description

4-Amino-1H-Indole-2-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique bifunctional structure, combining a reactive amino group and a carboxylic acid moiety on the indole scaffold, enabling diverse chemical modifications. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides with specific biological activity.
• Material Science Research: Serves as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Bioconjugation & Probe Development: Utilized in creating fluorescent probes, biomarkers, and other diagnostic reagents due to its modifiable functional groups.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in heterocyclic and indole chemistry.

Basic Information

Product Name	4-Amino-1H-Indole-2-Carboxylic Acid
CAS No.	933721-48-3
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	4-Amino-1H-indole-2-carboxylic acid; 4-Aminoindole-2-carboxylic acid; 2-Carboxy-4-aminoindole; 4-Amino-2-indolecarboxylic acid; 1H-Indole-2-carboxylic acid, 4-amino-; 933721-48-3; 4-Aminoindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.