Description

2-Chloro-1H-Benzimidazole-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals due to its reactive chloro and carboxylic acid functional groups. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Building block for developing new-generation fungicides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of organic ligands for metal-organic frameworks (MOFs) and functional polymers.
• Biochemical Research: Serves as a scaffold for designing enzyme inhibitors and molecular probes in life science research.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other specialty chemicals requiring the benzimidazole core structure.

Basic Information

Product Name	2-Chloro-1H-Benzimidazole-5-Carboxylic Acid
CAS No.	933710-78-2
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	2-Chloro-1H-benzimidazole-5-carboxylic acid; 5-Carboxy-2-chlorobenzimidazole; 2-Chloro-5-carboxybenzimidazole; 1H-Benzimidazole-5-carboxylic acid, 2-chloro-; 933710-78-2; 2-Chloro-1H-1,3-benzodiazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-1H-Benzimidazole-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.