Description

3,5-Bis(Ethoxycarbonyl)Phenylboronicacid is a specialized boronic acid derivative featuring dual ester functionalities, serving as a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating advanced organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly those containing biphenyl or terphenyl scaffolds common in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require specific aryl-aryl linkages.
• Material Science & OLED Development: Serves as a precursor for synthesizing organic semiconductors, light-emitting materials, and charge-transport layers in OLED (Organic Light-Emitting Diode) devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysts.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Chemical Research & Library Synthesis: A valuable reagent for medicinal chemistry and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3,5-Bis(Ethoxycarbonyl)Phenylboronicacid
CAS No.	932378-94-4
Molecular Formula	C13H17BO6
Molecular Weight	280.08 g/mol
Synonyms	(3,5-Diethoxycarbonylphenyl)boronic acid; 3,5-Bis(ethoxycarbonyl)benzeneboronic acid; [3,5-Bis(ethoxycarbonyl)phenyl]boronic acid; 3,5-Di(ethoxycarbonyl)phenylboronic acid; Boronic acid, B-[3,5-bis(ethoxycarbonyl)phenyl]-; 3,5-Dicarbethoxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Ethoxycarbonyl)Phenylboronicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and 1H/11B/13C NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.