Description

Methyl 5-(Trifluoromethoxy)-1H-Indazole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its indazole core and trifluoromethoxy substituent. This compound is essential for research and development in medicinal chemistry, offering a key building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies, agrochemical research facilities, and contract research organizations (CROs) engaged in developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Serves as a key scaffold for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Methyl 5-(Trifluoromethoxy)-1H-Indazole-3-Carboxylate
CAS No.	932041-12-8
Molecular Formula	C10H7F3N2O3
Molecular Weight	260.17 g/mol
Synonyms	5-(Trifluoromethoxy)-1H-indazole-3-carboxylic acid methyl ester; Methyl 5-(trifluoromethoxy)indazole-3-carboxylate; 1H-Indazole-3-carboxylic acid, 5-(trifluoromethoxy)-, methyl ester; 932041-12-8; MFCD22586533
EINECS	Contact for details

Quality Control

Our Methyl 5-(Trifluoromethoxy)-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.