Description

3-(4-Trifluoromethylbenzyl)-1,3-Dihydroindol-2-One is a high-value, fluorinated indolinone derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where its unique trifluoromethylbenzyl moiety is leveraged to modulate the physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted research.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme mechanisms or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-(4-Trifluoromethylbenzyl)-1,3-Dihydroindol-2-One
CAS No.	931927-97-8
Molecular Formula	C16H12F3NO
Molecular Weight	291.27 g/mol
Synonyms	3-[(4-Trifluoromethyl)benzyl]indolin-2-one; 3-(4-Trifluoromethylbenzyl)indolin-2-one; 2-Indolinone, 3-[(4-(trifluoromethyl)phenyl)methyl]-; 3-(4-(Trifluoromethyl)benzyl)-1,3-dihydro-2H-indol-2-one; 3-(4-Trifluoromethylbenzyl)-2-oxindole; 931927-97-8; 3-(alpha,alpha,α-Trifluoro-p-tolyl)methyl-2-oxindole
EINECS	Contact for details

Quality Control

Our production of 3-(4-Trifluoromethylbenzyl)-1,3-Dihydroindol-2-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.