Description

1,3-Dichloroisoquinoline-7-Sulfonyl Chloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its significance lies in its dual reactive sites—the sulfonyl chloride and dichlorinated isoquinoline moieties—which enable precise and efficient derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific isoquinoline-based scaffolds.
• Material Science Research: Serves as a precursor for creating functionalized polymers or organic electronic materials with tailored properties.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Sulfonamide Library Synthesis: The reactive sulfonyl chloride group is ideal for high-throughput parallel synthesis of diverse sulfonamide libraries for screening.

Basic Information

Product Name	1,3-Dichloroisoquinoline-7-Sulfonyl Chloride
CAS No.	930396-15-9
Molecular Formula	C9H4Cl3NO2S
Molecular Weight	296.56 g/mol
Synonyms	7-Chlorosulfonyl-1,3-dichloroisoquinoline; 1,3-Dichloro-7-isoquinolinesulfonyl chloride; 1,3-Dichloro-7-sulfonylchloride isoquinoline; Isoquinoline-7-sulfonyl chloride, 1,3-dichloro-; 930396-15-9; 1,3-Dichloroisoquinoline-7-sulfonylchloride
EINECS	Contact for details

Quality Control

Our 1,3-Dichloroisoquinoline-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.