Description

2-Oxo-2,3-Dihydro-1,3-Thiazole-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of the sulfonamide moiety, a key functional group for modulating biological activity and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying proteins and other biomolecules.
• Material Science Research: Building block for synthesizing functional polymers and advanced organic materials with specific sulfonated characteristics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for bespoke chemical synthesis services targeting complex molecular architectures.

Basic Information

Product Name	2-Oxo-2,3-Dihydro-1,3-Thiazole-5-Sulfonyl Chloride
CAS No.	930396-12-6
Molecular Formula	C3H2ClNO3S2
Molecular Weight	199.64 g/mol
Synonyms	5-Sulfonylchloride-2-oxo-2,3-dihydrothiazole; 1,3-Thiazole-5-sulfonyl chloride, 2,3-dihydro-2-oxo-; 2-Oxo-2,3-dihydrothiazole-5-sulfonyl chloride; 2-Oxothiazolidine-5-sulfonyl chloride; 5-Thiazolesulfonyl chloride, 2,3-dihydro-2-oxo-; Rhodanine-5-sulfonyl chloride; 2-Thioxo-4-thiazolidinone-5-sulfonyl chloride (tautomeric form)
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3-Dihydro-1,3-Thiazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.