Description

4-(1H-Indol-3-Yl)-3,6-Dihydropyridine-1(2H)-Carboxamide is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indole and dihydropyridine pharmacophores. This compound is of significant value for medicinal chemistry research and drug discovery programs targeting complex biological pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for potential drug candidates during pre-clinical and clinical stages.
• Biochemical Tool Compound: May be employed in biochemical assays to study enzyme inhibition or receptor modulation due to its privileged structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical sector.

Basic Information

Product Name	4-(1H-Indol-3-Yl)-3,6-Dihydropyridine-1(2H)-Carboxamide
CAS No.	929974-77-6
Molecular Formula	C14H15N3O
Molecular Weight	241.29 g/mol
Synonyms	1,2,3,6-Tetrahydro-4-(3-indolyl)pyridine-1-carboxamide; 4-(1H-Indol-3-yl)-1,2,3,6-tetrahydropyridine-1-carboxamide; 4-(Indol-3-yl)-3,6-dihydro-2H-pyridine-1-carboxamide; 929974-77-6; 4-(3-Indolyl)-1,2,3,6-tetrahydropyridine-1-carboxamide
EINECS	Contact for details

Quality Control

Every batch of 4-(1H-Indol-3-Yl)-3,6-Dihydropyridine-1(2H)-Carboxamide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each shipment to support your regulatory and research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.