Description

2-[3-(Trifluoromethyl)[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl]-1H-Indole is a high-value, complex heterocyclic compound featuring a fused triazolothiadiazole core and an indole moiety, distinguished by the presence of a trifluoromethyl group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D teams in the pharmaceutical and agrochemical sectors for the development of new active ingredients. The compound's structure suggests potential applications in creating molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazolothiadiazole and indole structures.
• Medicinal Chemistry Scaffold: Provides a core structure for combinatorial chemistry and high-throughput screening libraries to discover new pharmacophores.
• Organic Synthesis Reference Standard: Employed as a pure standard for analytical method development and validation in QC laboratories.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials due to its electron-deficient heterocyclic system.

Basic Information

Product Name	2-[3-(Trifluoromethyl)[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl]-1H-Indole
CAS No.	929831-76-5
Molecular Formula	C₁₂H₆F₃N₅S
Molecular Weight	309.27 g/mol
Synonyms	1H-Indole, 2-[3-(trifluoromethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-; 2-(3-(Trifluoromethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-1H-indole; 6-(1H-Indol-2-yl)-3-(trifluoromethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole; 929831-76-5; 3-Trifluoromethyl-6-(1H-indol-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
EINECS	Contact for details

Quality Control

Every batch of our 2-[3-(Trifluoromethyl)[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazol-6-Yl]-1H-Indole is manufactured and tested under a strict cGMP-compliant quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong alkalis and fluorides, as indicated by its chemical properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.