Description

tert-Butyl 5-Bromo-3-(Trifluoromethyl)-1H-Indazole-1-Carboxylate is a high-value, multi-functional chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex chemical syntheses. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indazole and trifluoromethyl motifs for enhanced biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Provides a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo substituent.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical spaces.
• Ligand & Catalyst Development: Used in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	tert-Butyl 5-Bromo-3-(Trifluoromethyl)-1H-Indazole-1-Carboxylate
CAS No.	929617-37-8
Molecular Formula	C₁₃H₁₂BrF₃N₂O₂
Molecular Weight	365.15 g/mol
Synonyms	1-BOC-5-Bromo-3-(trifluoromethyl)-1H-indazole; 5-Bromo-3-(trifluoromethyl)-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 5-bromo-3-(trifluoromethyl)indazole-1-carboxylate; 5-Bromo-3-trifluoromethyl-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-5-bromo-3-(trifluoromethyl)-1H-indazole; BOC-5-Bromo-3-CF3-indazole; 929617-37-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromo-3-(Trifluoromethyl)-1H-Indazole-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.