Description

(R)-Methyl 5-(6-(Hydroxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure featuring a benzimidazole and a thiophene core. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring chiral specificity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially those targeting specialized receptor pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and neurology research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and development of new APIs that leverage its specific benzimidazole-thiophene scaffold for biological activity.
• Biochemical Research: Employed as a reference standard or a probe molecule in biochemical assays and pharmacological studies to investigate enzyme inhibition or receptor binding.
• Process Chemistry & Scale-Up: Utilized in process optimization and scale-up studies within contract research and manufacturing organizations (CROs/CMOs) to develop efficient synthetic routes.
• Academic Research: Used in university and institutional laboratories for synthetic organic chemistry projects and the exploration of new heterocyclic compounds.

Basic Information

Product Name	(R)-Methyl 5-(6-(Hydroxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate
CAS No.	929095-39-6
Molecular Formula	C23H20F3N2O4S
Molecular Weight	477.48 g/mol
Synonyms	Methyl (R)-5-[6-(hydroxymethyl)-1H-benzimidazol-1-yl]-3-[1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxylate; (R)-5-(6-(Hydroxymethyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylic acid methyl ester; 929095-39-6; Benzimidazole-thiophene carboxylate intermediate; CAS 929095-39-6
EINECS	Contact for details

Quality Control

Our (R)-Methyl 5-(6-(Hydroxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with exacting standards for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.